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Article

Single nucleotide polymorphisms of Helicobacter pylori dupA that lead to premature stop codons.

Helicobacter - 1 Jun 2012

Moura Sílvia B, Costa Rafaella F A, Anacleto Charles, Rocha Gifone A, Rocha Andreia M C, Queiroz Dulciene M M

Abstract excerpt

BACKGROUND: The detection of the putative disease-specific Helicobacter pylori marker duodenal ulcer promoting gene A (dupA) is currently based on PCR detection of jhp0917 and jhp0918 that form the gene. However, mutations that lead to premature stop codons that split off the dupA leading to truncated products cannot be evaluated by PCR. METHODS: We directly sequence the complete dupA of 75 dupA-positive strains...

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Source

Identifiers

PMID: 22515354
DOI: 10.1111/j.1523-5378.2011.00933.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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