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Article

Functional heterogeneity of mesenchymal stem cells: Implications for cell therapy

17 Apr 2012

Abstract excerpt

The term mesenchymal stem cell (MSCs) was adopted in the 1990s to describe a population of bone-marrow-derived cells that demonstrated the capacity for tri-lineage differentiation at a clonal level. Research conducted during the ensuing decades has demonstrated that MSCs fulfill many functions in addition to connective tissue progenitors including contributing to the HSC niche and regulating the function of...

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PMID: 22511358
DOI: 10.1002/jcb.24166

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