Biochemical Heterogeneity of Mesenchymal Stem Cell Populations: Clues to their Therapeutic Efficacy

Abstract excerpt

Mesenchymal stem cells (MSCs) were initially identified by their capacity to differentiate into connective tissue cell types. In the past decade MSCs were also shown to exhibit unexpected plasticity, which was thought to account for their broad therapeutic efficacy in animal models of disease and human clinical trials. More recent evidence indicates that their capacity to alter the microenvironment via secretion...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mesenchymal stem cell research
• Share to MicroRNA in disease regulation
• Share to RNA Interference and Gene Delivery