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Choline Supplementation and <scp>DNA</scp> Methylation in the Hippocampus and Prefrontal Cortex of Rats Exposed to Alcohol During Development

17 Apr 2012

Abstract excerpt

BACKGROUND: Some of the most frequent deficits seen in children with fetal alcohol spectrum disorders (FASD) and in animal models of FASD are spatial memory impairments and impaired executive functioning, which are likely related to alcohol-induced alterations of the hippocampus and prefrontal cortex (PFC), respectively. Choline, a nutrient supplement, has been shown in a rat model to ameliorate some of alcohol's...

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PMID: 22509990
DOI: 10.1111/j.1530-0277.2012.01784.x

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