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Article

Generation of kidney from pluripotent stem cells via blastocyst complementation.

The American journal of pathology - 1 Jun 2012

Usui Jo-ichi, Kobayashi Toshihiro, Yamaguchi Tomoyuki, Knisely A S, Nishinakamura Ryuichi, Nakauchi Hiromitsu

Abstract excerpt

Because a shortage of donor organs has been a major obstacle to the expansion of organ transplantation programs, the generation of transplantable organs is among the ultimate goals of regenerative medicine. However, the complex cellular interactions among and within tissues that are required for organogenesis are difficult to recapitulate in vitro. As an alternative, we used blastocyst complementation to generate...

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Identifiers

PMID: 22507837
DOI: 10.1016/j.ajpath.2012.03.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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