Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal epidermal barrier in the pathogenesis of psoriasis.

Clinics in dermatology - 1 Jan 2000

Wolf Ronni, Orion Edith, Ruocco Eleonora, Ruocco Vincenzo

Abstract excerpt

Almost 2 decades ago, Williams and Elias suggested a unifying concept for the pathogenesis of disorders of cornification, according to which the integrity of the epidermal barrier and its effective function is an important factor in the regulation of epidermal DNA synthesis. Interference with the barrier integrity or function will result in epidermal hyperplasia and may be the primary event leading to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cell Division
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Gene Expression

Share to Genome-Wide Association Study

Share to Permeability

Share to Psoriasis

Source

Identifiers

PMID: 22507047
DOI: 10.1016/j.clindermatol.2011.08.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal epidermal barrier in the pathogenesis of psoriasis.PMID 22507047Read ↗

Skin barrier in atopic dermatitisSemantic proximity Read ↗

Potential Role of the Epidermal Differentiation Complex in the Pathogenesis of PsoriasisSemantic proximity Read ↗

Epidermal barrier in hereditary ichthyoses, atopic dermatitis, and psoriasis.Semantic proximity Read ↗

Genetics of Psoriasis: Evidence for Epistatic Interaction between Skin Barrier Abnormalities and Immune DeviationSemantic proximity Read ↗

Updated Perspectives on Keratinocytes and Psoriasis: Keratinocytes are More Than Innocent BystandersSemantic proximity Read ↗

Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases.Semantic proximity Read ↗

[What do we know about pathogenesis of psoriasis?].Semantic proximity Read ↗

Epidermal Differentiation in Barrier Maintenance and Wound HealingSemantic proximity Read ↗

The stratum corneum barrier: impaired function in relation to associated lipids and proteinsSemantic proximity Read ↗

Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients.Semantic proximity Read ↗

The role of barrier genes in epidermal malignancy.Semantic proximity Read ↗

Ichthyosis: A Road Model for Skin Research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.