Article
Physiopathology and diagnosis of nephrogenic diabetes insipidus.
Annales d'endocrinologie - 1 Apr 2012
Devuyst Olivier
Abstract excerpt
Nephrogenic diabetes insipidus (NDI) is caused by an improper response of the kidney to the antidiuretic hormone arginine vasopressin (AVP), leading to a decreased ability to concentrate urine which results in polyuria and polydipsia. The clinical diagnosis of NDI relies on demonstration of subnormal ability to concentrate urine despite the presence of AVP. NDI is most commonly acquired, secondary to kidney...
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