Article
Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China.
Virology journal - 14 Apr 2012
Yong-Lin Yang, Qiang Fu, Ming-Shun Zhang, Jie Cai, Gui-Ming Ma, Zu-Hu Huang, Xu-Bing Cai
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) is still one of the serious infectious risks for the blood transfusion safety in China. One plausible reason is the emergence of the variants in the major antigenic alpha determinant within the major hydrophilic region (MHR) of hepatitis B surface antigen (HBsAg), which have been assumed to evade the immune surveillance and pose a challenge to the disease diagnosis. It is well...
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