Article
Conserved haplotype blocks within the sheep MHC and low SNP heterozygosity in the Class IIa subregion.
Animal genetics - 1 Aug 2012
Lee C Y, Qin J, Munyard K A, Siva Subramaniam N, Wetherall J D, Stear M J, Groth D M
Abstract excerpt
This report describes single-nucleotide polymorphisms (SNPs) in the sheep major histocompatibility complex (MHC) class II and class III regions and provides insights into the internal structure of this important genomic complex. MHC haplotypes were deduced from sheep family trios based on genotypes from 20 novel SNPs representative of the class II region and 10 previously described SNPs spanning the class III...
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