A common genetic variant at 15q25 modifies the associations of maternal smoking during pregnancy with fetal growth: the generation R study.

doi:10.1371/journal.pone.0034584

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Article

A common genetic variant at 15q25 modifies the associations of maternal smoking during pregnancy with fetal growth: the generation R study.

PloS one - 1 Jan 2012

Leermakers Elisabeth T M, Taal H Rob, Bakker Rachel, Steegers Eric A P, Hofman Albert, Jaddoe Vincent W V

Abstract excerpt

OBJECTIVE: Maternal smoking during pregnancy is associated with fetal growth retardation. We examined whether a common genetic variant at chromosome 15q25 (rs1051730), which is known to be involved in nicotine metabolism, modifies the associations of maternal smoking with fetal growth characteristics. METHODS: This study was performed in 3,563 European mothers participating in a population-based prospective...

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Identifiers

PMID: 22496830
DOI: 10.1371/journal.pone.0034584
PMCID: PMC3319619

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