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Article

Human Galectin 3 Binding Protein Interacts with Recombinant Adeno-Associated Virus Type 6

12 Apr 2012

Abstract excerpt

Recombinant adeno-associated viruses (rAAVs) hold enormous potential for human gene therapy. Despite the well-established safety and efficacy of rAAVs for in vivo gene transfer, there is still little information concerning the fate of vectors in blood following systemic delivery. We screened for serum proteins interacting with different AAV serotypes in humans, macaques, dogs, and mice. We report that serotypes...

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PMID: 22496229
DOI: 10.1128/jvi.00297-12

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