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Genetic Analysis of Cytomegalovirus in Malignant Gliomas

12 Apr 2012

Abstract excerpt

Human cytomegalovirus (HCMV) has been found in malignant gliomas at variable frequencies with efforts to date focused on characterizing the role(s) of single gene products in disease. Here, we reexamined the HCMV prevalence in malignant gliomas using different methods and began to dissect the genetics of HCMV in tumors. HCMV DNA was found in 16/17 (94%) tumor specimens. Viral DNA copy numbers were found to be low...

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PMID: 22496213
DOI: 10.1128/jvi.00015-12

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