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[Mutation screening of LKB1 gene in familial Peutz-Jeghers syndrome patients].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2012

Chen Chun-yan, Zhang Xiao-mei, Wang Fang-yu, Wang Zhen-kai, Zhu Ming, Ma Guo-jian, Zhang Yuan-ying, Jin Xin-xin, Shi Hui, Liu Jiong

Abstract excerpt

OBJECTIVE: To screen for potential mutations of LKB1 gene in Chinese familial Peutz-Jeghers syndrome (PJS) patients and analyze their clinical manifestations. METHODS: Eleven PJS families were collected and genomic DNA of peripheral blood was extracted. Typically mucosal pigmentation and hamartomatous polyps were present in all 11 probands. Mutation screening of the probands were carried out by PCR and direct...

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Identifiers

PMID: 22487816
DOI: 10.3760/cma.j.issn.1003-9406.2012.02.001

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Source receipt: pubmed, retrieved 7 Sept 2026.

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