The family of mammalian small heat shock proteins (HSPBs): implications in protein deposit diseases and motor neuropathies.

Abstract excerpt

A number of neurological and muscular disorders are characterized by the accumulation of aggregate-prone proteins and are referred to as protein deposit or protein conformation diseases. Besides some sporadic forms, most of them are genetically inherited in an autosomal dominant manner, although recessive forms also exist. Although genetically very heterogeneous, some of these diseases are the result of mutations...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apoptosis
• Share to Genetic Neurodegenerative Diseases