Article
Application of co-expressed genes to articular cartilage: new hope for the treatment of osteoarthritis (review).
Molecular medicine reports - 1 Jul 2012
Wan Rong, Hu Jiong, Zhou Qi, Wang Jun, Liu Peiyi, Wei Yiyong
Abstract excerpt
Osteoarthritis (OA), with a high prevalence and economic impact, is a progressive diarthrodial joint disease that substantially reduces quality of life and is mainly characterized by degradation of the extracellular matrix (ECM) and the loss of a chondrogenic phenotype in articular cartilage. Strategic targeting of therapeutic genes to OA cartilage may offer potent...
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