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Patterns of Early Gut Colonization Shape Future Immune Responses of the Host

27 Mar 2012

Abstract excerpt

The most important trigger for immune system development is the exposure to microbial components immediately after birth. Moreover, targeted manipulation of the microbiota can be used to change host susceptibility to immune-mediated diseases. Our aim was to analyze how differences in early gut colonization patterns change the composition of the resident microbiota and future immune system reactivity. Germ-free...

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PMID: 22479515
DOI: 10.1371/journal.pone.0034043

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