Article
Increased risk of stroke in oral contraceptive users carried replicated genetic variants: a population-based case-control study in China.
Human genetics - 1 Aug 2012
Wang Chun, Li Ying, Li Huiqiao, Sun Tao, Jin Guangfu, Sun Zhiming, Zhou Jian, Ba Lei, Huang Zhizheng, Bai Jianling
Abstract excerpt
Combined oral contraceptives (COC) use is a unique risk factor for stroke in women, and may modify the associations between genetic polymorphisms and stroke. To investigate whether the genetic variants identified in a recent genome-wide association study (GWAS) could be replicated in Chinese women, as well as, whether related risk was different in COC users, 451 stroke cases and 831 age- and region-matched...
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