Article
COC use, ACE/AGT gene polymorphisms, and risk of stroke.
Pharmacogenetics and genomics - 1 May 2010
Li Ying, Chen Feng, Zhou Lifeng, Coulter David, Chen Cheng, Sun Zhiming, Chen Jianfeng, Pan Hongxin, Wu Yulin, Zhou Jian, Ba Lei, Zhao Jinna, Shen Hongbing
Abstract excerpt
OBJECTIVES: To clarify the effects of the association between combined oral contraceptives (COC) use and ACE/AGT gene on stroke risk, and to undertake a preliminarily study of the molecular mechanism of the association between COC exposure and predisposing genes of hypertension on the increased risk of stroke. METHODS: This study was a multi-center case-control study based on the population of 25 towns in the...
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