Article
Infection, mutation, and cancer evolution.
Journal of molecular medicine (Berlin, Germany) - 1 May 2012
Ewald Paul W, Swain Ewald Holly A
Abstract excerpt
An understanding of oncogenesis can be fostered by an integration of mechanistic studies with evolutionary considerations, which help explain why these mechanisms occur. This integration emphasizes infections and mutations as joint essential causes for many cancers. It suggests that infections may play a broader causal role in oncogenesis than has been generally appreciated. An evolutionary perspective also...
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