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Article

PROKR2 Variants in Multiple Hypopituitarism with Pituitary Stalk Interruption

1 Apr 2012

Abstract excerpt

CONTEXT: Pituitary stalk interruption represents a frequent feature of congenital hypopituitarism, but only rare cases have been assigned to a known genetic cause. OBJECTIVE: Using a candidate gene approach, we tested several genes as potential causes of hypopituitarism with pituitary stalk interruption. We hypothesized that ectopic posterior pituitary may be a consequence of defective neuronal axon projections...

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PMID: 22466334
DOI: 10.1210/jc.2011-3056

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