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Article

Antisense-mediated exon skipping to reframe transcripts.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Turczynski Sandrina, Titeux Matthias, Pironon Nathalie, Hovnanian Alain

Abstract excerpt

Numerous genetic disorders are caused by loss-of-function mutations that disrupt the open reading frame of the gene either by nonsense or by frameshift (insertion, deletion, indel, or splicing) mutations. Most of the time, the result is the absence of functional protein synthesis due to mRNA degr...

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Share to Collagen Type VII
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22454065
DOI: 10.1007/978-1-61779-767-5_15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22454065-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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