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Article

Study of the electrostatic effects of mutations on the surface of dehaloperoxidase-hemoglobin A.

Biochemical and biophysical research communications - 20 Apr 2012

Zhao Junjie, Rowe Jennifer, Franzen Jocelyn, He Chi, Franzen Stefan

Abstract excerpt

Point mutations of dehaloperoxidase-hemoglobin A (DHP A) that affect the surface charge have been prepared to study the interaction between DHP A with its substrate 2,4,6-trichlorophenol (TCP). Kinetic studies of these surface mutations showed a correlation, in which the more positively charged mutants have increased catalytic efficiency compared with wild type DHP A. As a result, the hypothesis of this study is...

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PMID: 22450312
DOI: 10.1016/j.bbrc.2012.03.053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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