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Article

High frequency of the expanded C9ORF72 hexanucleotide repeat in familial and sporadic Greek ALS patients.

Neurobiology of aging - 1 Aug 2012

Mok Kin Y, Koutsis Georgios, Schottlaender Lucia V, Polke James, Panas Marios, Houlden Henry

Abstract excerpt

An intronic expansion of a hexanucleotide GGGGCC repeat in the C9ORF72 gene has recently been shown to be an important cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in familial and sporadic cases. The frequency has only been defined in a small number of populations where the highest sporadic rate was identified in Finland (21.1%) and the lowest in mainland Italy (4.1%). We...

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Identifiers

PMID: 22445326
DOI: 10.1016/j.neurobiolaging.2012.02.021
PMCID: PMC3657168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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