Article
Attachment of capsular polysaccharide to the cell wall in Streptococcus pneumoniae.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jun 2012
Eberhardt Alice, Hoyland Christopher N, Vollmer Daniela, Bisle Stephanie, Cleverley Robert M, Johnsborg Ola, Håvarstein Leiv S, Lewis Richard J, Vollmer Waldemar
Abstract excerpt
Streptococcus pneumoniae protects itself from components of the human immune defense system by a thick polysaccharide capsule, which in most serotypes is covalently attached to the cell wall peptidoglycan. Members of the LytR-Cps2A-Psr (LCP) protein family have recently been implicated in the attachment of anionic polymers to peptidoglycan in Gram-positive bacteria, based on genetic evidence from Bacillus...
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