Article
A widespread family of bacterial cell wall assembly proteins.
The EMBO journal - 30 Sept 2011
Kawai Yoshikazu, Marles-Wright Jon, Cleverley Robert M, Emmins Robyn, Ishikawa Shu, Kuwano Masayoshi, Heinz Nadja, Bui Nhat Khai, Hoyland Christopher N, Ogasawara Naotake, Lewis Richard J, Vollmer Waldemar, Daniel Richard A, Errington Jeff
Abstract excerpt
Teichoic acids and acidic capsular polysaccharides are major anionic cell wall polymers (APs) in many bacteria, with various critical cell functions, including maintenance of cell shape and structural integrity, charge and cation homeostasis, and multiple aspects of pathogenesis. We have identified the widespread LytR-Cps2A-Psr (LCP) protein family, of previously unknown function, as novel enzymes required for AP...
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