Article
First detection of Hb Taybe [α38(C3) or α39(C4) Thr→0 (α1)] in an Italian child.
Hemoglobin - 1 Jan 2012
Paglietti Maria Elisabetta, Sollaino Maria Carla, Loi Daniela, Barella Susanna, Desogus Maria Franca, Galanello Renzo
Abstract excerpt
Hb Taybe [α38(C3) or α39(C4) Thr→0 (α1)] is an unstable hemoglobin (Hb) variant caused by a deletion of a threonine residue at codon 39 of the α1-globin chain. Usually asymptomatic or with minimal hematological abnormalities in the heterozygous state, Hb Taybe becomes clinically evident in compound heterozygosity with α-thalassemia (α-thal) or in homozygous patients. To date, Hb Taybe has been described in...
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