Article
Hb TAYBE: clinical and morphological findings IN 43 patients.
European journal of haematology - 1 Aug 2016
Koren Ariel, Levin Carina, Zalman Luci, Palmor Haya, Filon Dvora, Chubar Evgeny, Resnitzky Peretz, Bennett Michael
Abstract excerpt
UNLABELLED: Hereditary sequence variants in globin genes are usually silent and are rarer in α-globin chains than β-globin chains. Some may lead to an unstable protein with a hemolytic or thalassemic phenotype. Hb Taybe is an unstable α-chain hemoglobin variant caused by the deletion of a threonine residue at codon 38 or 39 of the α1 globin gene. This deletion results in a structural abnormality that affects the...
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