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Article

Contribution of myostatin gene polymorphisms to normal variation in lean mass, fat mass and peak BMD in Chinese male offspring.

Acta pharmacologica Sinica - 1 May 2012

Yue Hua, He Jin-wei, Zhang Hao, Wang Chun, Hu Wei-wei, Gu Jie-mei, Ke Yao-hua, Fu Wen-zhen, Hu Yun-qiu, Li Miao, Liu Yu-juan, Wu Song-hua, Zhang Zhen-lin

Abstract excerpt

AIM: Myostatin gene is a member of the transforming growth factor-β (TGF-β) family that negatively regulates skeletal muscle growth. Genetic polymorphisms in Myostatin were found to be associated with the peak bone mineral density (BMD) in Chinese women. The purpose of this study was to investigate whether myostatin played a role in the normal variation in peak BMD, lean mass (LM), and fat mass (FM) of Chinese...

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Identifiers

PMID: 22426697
DOI: 10.1038/aps.2012.12
PMCID: PMC4010361

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