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Article

Genetics of complex diseases: variations on a theme.

Medical hypotheses - 1 Jun 2012

Mellerup Erling, Møller Gert Lykke, Koefoed Pernille

Abstract excerpt

A complex disease with an inheritable component is polygenic, meaning that several different changes in DNA are the genetic basis for the disease. Such a disease may also be genetically heterogeneous, meaning that independent changes in DNA, i.e. various genotypes, can be the genetic basis for the disease. Each of these genotypes may be characterized by specific combinations of key genetic changes. It is...

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Identifiers

PMID: 22424717
DOI: 10.1016/j.mehy.2012.02.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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