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Article

The relationship between EMT, CD44high /EGFRlow phenotype, and treatment response in head and neck cancer cell lines.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Oct 2016

Johansson Ann-Charlotte, La Fleur Linnea, Melissaridou Styliani, Roberg Karin

Abstract excerpt

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) tumors are often therapy resistant and may originate from cancer stem cells or tumor cells with an epithelial-to-mesenchymal transition (EMT) phenotype. The aim of this study was to characterize HNSCC cell lines with regard to EMT profile and to investigate the influence of EMT on the response to treatment. METHODS: mRNA expression of the EMT-associated...

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Source

Identifiers

PMID: 26757432
DOI: 10.1111/jop.12423

Genes

EGFR
TWIST1
CDH1
CDH2
FOXC2
VIM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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