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Hair‐inducing ability of human dermal papilla cells cultured under Wnt/β‐catenin signalling activation

27 Jan 2012

Abstract excerpt

It is well known that dermal papilla cells (DPCs) play crucial roles in hair follicle induction. In this study, we examined whether Wnt/β-catenin activation results in maintenance of the hair-inducing ability of human DPCs. Expression of DPC marker genes was maintained under Wnt/β-catenin signalling stimulation by GSK-3β inhibition. Furthermore, human DPCs showed constant hair induction when transplanted with...

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PMID: 22417309
DOI: 10.1111/j.1600-0625.2012.01458.x

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