Article
DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees.
Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2012
Foret Sylvain, Kucharski Robert, Pellegrini Matteo, Feng Suhua, Jacobsen Steven E, Robinson Gene E, Maleszka Ryszard
Abstract excerpt
In honey bees (Apis mellifera), the development of a larva into either a queen or worker depends on differential feeding with royal jelly and involves epigenomic modifications by DNA methyltransferases. To understand the role of DNA methylation in this process we sequenced the larval methylomes in both queens and workers. We show that the number of differentially methylated genes (DMGs) in larval head is...
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