Article
Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity.
Journal of gastroenterology and hepatology - 1 Sept 2012
Adams Leon A, Marsh Julie A, Ayonrinde Oyekoya T, Olynyk John K, Ang Wei Q, Beilin Lawrence J, Mori Trevor, Palmer Lyle J, Oddy Wendy W, Lye Steven J, Pennell Craig E
Abstract excerpt
BACKGROUND AND AIM: Environmental factors including excessive caloric intake lead to disordered lipid metabolism and fatty liver disease (FLD). However, FLD demonstrates heritability suggesting genetic factors are also important. We aimed to use a candidate gene approach to examine the association between FLD and single nucleotide polymorphisms (SNPs) in lipid metabolism genes in the adolescent population-based...
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