Detection of IL28B SNP DNA from buccal epithelial cells, small amounts of serum, and dried blood spots.

doi:10.1371/journal.pone.0033000

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Article

Detection of IL28B SNP DNA from buccal epithelial cells, small amounts of serum, and dried blood spots.

PloS one - 1 Jan 2012

Halfon Philippe, Ouzan Denis, Khiri Hacène, Pénaranda Guillaume, Castellani Paul, Oulès Valerie, Kahloun Asma, Amrani Nolwenn, Fanteria Lise, Martineau Agnès, Naldi Lou, Bourlière Marc

Abstract excerpt

BACKGROUND & AIMS: Point mutations in the coding region of the interleukin 28 gene (rs12979860) have recently been identified for predicting the outcome of treatment of hepatitis C virus infection. This polymorphism detection was based on whole blood DNA extraction. Alternatively, DNA for genetic diagnosis has been derived from buccal epithelial cells (BEC), dried blood spots (DBS), and genomic DNA from serum....

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PMID: 22412970
DOI: 10.1371/journal.pone.0033000
PMCID: PMC3296767

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