Article
Association of angiotensin-converting enzyme functional gene I/D polymorphism with amnestic mild cognitive impairment.
Neuroscience letters - 11 Apr 2012
Zhang Zhengsheng, Deng Linglong, Yu Hui, Shi Yongmei, Bai Feng, Xie Chunming, Yuan Yonggui, Jia Jianping, Zhang Zhijun
Abstract excerpt
The relationship between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and serum ACE activity, as well as amnestic mild cognitive impairment (aMCI), was investigated. The study recruited 90 aMCI patients and 90 matched healthy controls. All subjects underwent an extensive assessment of cognitive function. The ACE gene I/D genotype was determined by polymerase chain reaction. Serum...
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