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Article

Clinical-grade varicella zoster virus-specific T cells produced for adoptive immunotherapy in hemopoietic stem cell transplant recipients.

Cytotherapy - 1 Jul 2012

Blyth Emily, Gaundar Shivashni S, Clancy Leighton, Simms Renee M, Bilmon Ian, Micklethwaite Kenneth P, Gottlieb David J

Abstract excerpt

BACKGROUND AIMS: Varicella zoster virus (VZV) causes life-long latent infection in healthy individuals, which reactivates in 10-68% of stem cell transplant patients. Reconstituting immunity through adoptive transfer of T cells specific for VZV may aid in the prophylaxis and treatment of VZV infections. The potential for generating T cells specific for VZV using a clinically approved VZV vaccine strain was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

Share to Herpes Zoster

Share to Herpesvirus 3, Human

Share to Immunotherapy, Adoptive

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to T-Lymphocytes, Cytotoxic

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Identifiers

PMID: 22404084
DOI: 10.3109/14653249.2012.663486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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