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Deep learning-based pathway-centric approach to characterize recurrent hepatocellular carcinoma after liver transplantation

5 Jun 2024

Abstract excerpt

BACKGROUND: Liver transplantation (LT) is offered as a cure for Hepatocellular carcinoma (HCC), however 15-20% develop recurrence post-transplant which tends to be aggressive. In this study, we examined the transcriptome profiles of patients with recurrent HCC to identify differentially expressed genes (DEGs), the involved pathways, biological functions, and potential gene signatures of recurrent HCC...

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PMID: 38840185
DOI: 10.1186/s40246-024-00624-6

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