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Article

1P19Q loss but not IDH1 mutations influences WHO grade II gliomas spontaneous growth.

Journal of neuro-oncology - 1 May 2012

Gozé Catherine, Bezzina Charlotte, Gozé Eric, Rigau Valérie, Maudelonde Thierry, Bauchet Luc, Duffau Hugues

Abstract excerpt

Mutations at the codon 132 in the isocitrate dehydrogenase 1 (IDH1) gene occur early, with a high frequency, in World Health Organization (WHO) grade II gliomas. We investigated the impact of IDH1 mutations on spontaneous glioma growth rate, known to be an early prognostic factor.The mean tumor diameter was assessed on the first MRI performed at diagnosis and on a second MRI, performed immediately before surgery,...

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Source

Identifiers

PMID: 22392125
DOI: 10.1007/s11060-012-0831-6

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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