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Article

Study of leptin levels and gene polymorphisms in patients with central precocious puberty.

Pediatric research - 1 Apr 2012

Su Pen-Hua, Yang Shun-Fa, Yu Ju-Shan, Chen Suh-Jen, Chen Jia-Yuh

Abstract excerpt

INTRODUCTION: Three single-nucleotide polymorphisms (SNPs) in the leptin (LEP) or leptin receptor (LEPR) genes were assessed for their association with central precocious puberty (CPP). RESULTS: The control group with the A/G SNP at LEPR 223 or A/G SNP at LEPR 109 exhibited significantly higher peak luteinizing hormone (LH) levels. The leptin level in the CPP group was significantly higher than that in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22391636
DOI: 10.1038/pr.2011.69

Genes

LEPR
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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