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Genetic and epigenetic properties of mouse male germline stem cells during long-term culture

18 Aug 2005

Abstract excerpt

Although stem cells are believed to divide infinitely by self-renewal division, there is little evidence that demonstrates their infinite replicative potential. Spermatogonial stem cells are the founder cell population for spermatogenesis. Recently, in vitro culture of spermatogonial stem cells was described. Spermatogonial stem cells can be expanded in vitro in the presence of glial cell line-derived...

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PMID: 16107472
DOI: 10.1242/dev.02004

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