Article
[Hereditary neuroendrocrine tumors. Multiple endocrine neoplasia type 1 and 2].
Der Internist - 1 Apr 2012
Rinke A, Galan S R, Fendrich V, Kann P H, Bartsch D K, Gress T M
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal-dominant hereditary disease characterized by the occurrence of tumors of the parathyroids, duodenum and/or pancreas, and anterior pituitary. The syndrome is caused by germline mutations of the MEN1 tumor suppressor gene. The identification of the causative mutations is of paramount importance for the long-term management of affected individuals and their...
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