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p53 at the crossroads between cancer and neurodegeneration.

Free radical biology & medicine - 1 May 2012

Lanni Cristina, Racchi Marco, Memo Maurizio, Govoni Stefano, Uberti Daniela

Abstract excerpt

Aging, dementia, and cancer share a critical set of altered cellular functions in response to DNA damage, genotoxic stress, and other insults. Recent data suggest that the molecular machinery involved in maintaining neural function in neurodegenerative disease may be shared with oncogenic pathways. Cancer and neurodegenerative diseases may be influenced by common signaling pathways regulating the balance of cell...

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PMID: 22387179
DOI: 10.1016/j.freeradbiomed.2012.02.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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