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Autophagy Prior to Chondrocyte Cell Death During the Degeneration of Meckel's Cartilage

27 Feb 2012

Abstract excerpt

The central portion of Meckel's cartilage degenerates almost immediately after birth. Whether autophagy is involved in this process remains unclear. Thus, to explore the role of autophagy during this process, we have detected the expression of autophagy and apoptosis-related markers in embryonic mice. In E15, Beclin1 and LC3 expressions were weak and negative in Meckel's cartilage, respectively. In E16,...

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PMID: 22371349
DOI: 10.1002/ar.22433

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