Article
Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy.
Molecular medicine (Cambridge, Mass.) - 9 May 2012
Folkersen Lasse, Persson Jonas, Ekstrand Johan, Agardh Hanna E, Hansson Göran K, Gabrielsen Anders, Hedin Ulf, Paulsson-Berne Gabrielle
Abstract excerpt
Classic risk factors, including age, smoking, serum cholesterol, diabetes and blood pressure, constitute the basis of present risk prediction models but fail to identify all individuals at risk. The objective of this study was to investigate if genomic and transcriptional patterns improve prediction of ischemic events in patients with established carotid artery disease. Genotype and gene expression profiles were...
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