Article
Evolutionary genetics of the human Rh blood group system.
Human genetics - 1 Jul 2012
Perry George H, Xue Yali, Smith Richard S, Meyer Wynn K, Calışkan Minal, Yanez-Cuna Omar, Lee Arthur S, Gutiérrez-Arcelus María, Ober Carole, Hollox Edward J, Tyler-Smith Chris, Lee Charles
Abstract excerpt
The evolutionary history of variation in the human Rh blood group system, determined by variants in the RHD and RHCE genes, has long been an unresolved puzzle in human genetics. Prior to medical treatments and interventions developed in the last century, the D-positive (RhD positive) children of D-negative (RhD negative) women were at risk for hemolytic disease of the newborn, if the mother produced anti-D...
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