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Article

Structural and biochemical characterization of glycoside hydrolase family 79 β-glucuronidase from Acidobacterium capsulatum.

The Journal of biological chemistry - 20 Apr 2012

Michikawa Mari, Ichinose Hitomi, Momma Mitsuru, Biely Peter, Jongkees Seino, Yoshida Makoto, Kotake Toshihisa, Tsumuraya Yoichi, Withers Stephen G, Fujimoto Zui, Kaneko Satoshi

Abstract excerpt

We present the first structure of a glycoside hydrolase family 79 β-glucuronidase from Acidobacterium capsulatum, both as a product complex with β-D-glucuronic acid (GlcA) and as its trapped covalent 2-fluoroglucuronyl intermediate. This enzyme consists of a catalytic (β/α)(8)-barrel domain and a β-domain with irregular Greek key motifs that is of unknown function. The enzyme showed β-glucuronidase activity and...

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Identifiers

PMID: 22367201
DOI: 10.1074/jbc.M112.346288
PMCID: PMC3340155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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