Article
Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells.
Journal of cell science - 1 Apr 2012
Gayraud-Morel Barbara, Chrétien Fabrice, Jory Aurélie, Sambasivan Ramkumar, Negroni Elisa, Flamant Patricia, Soubigou Guillaume, Coppée Jean-Yves, Di Santo James, Cumano Ana, Mouly Vincent, Tajbakhsh Shahragim
Abstract excerpt
Skeletal muscle stem cell fate in adult mice is regulated by crucial transcription factors, including the determination genes Myf5 and Myod. The precise role of Myf5 in regulating quiescent muscle stem cells has remained elusive. Here we show that most, but not all, quiescent satellite cells expr...
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