Article
Polymorphisms in the gene that encodes the iron transport protein ferroportin 1 influence susceptibility to tuberculosis.
The Journal of infectious diseases - 1 Apr 2012
Baker Meghan A, Wilson Douglas, Wallengren Kristina, Sandgren Andreas, Iartchouk Oleg, Broodie Nisha, Goonesekera Sunali D, Sabeti Pardis C, Murray Megan B
Abstract excerpt
BACKGROUND: We studied the association between iron intake and polymorphisms in the iron transporter gene SLC40A1 and the risk of tuberculosis. METHODS: We compared iron intake, the frequency of SLC40A1 mutations, and interactions among these variables among 98 tuberculosis patients and 125 controls in Kwazulu-Natal, South Africa. RESULTS: Four SLC40A1 single-nucleotide polymorphisms (SNPs) were associated with...
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