Article
Association analysis of genetic variants in microRNA networks and gastric cancer risk in a Chinese Han population.
Journal of cancer research and clinical oncology - 1 Jun 2012
Zhou Yuan, Du Wei-Dong, Chen Gang, Ruan Jian, Xu Song, Zhou Fu-Sheng, Zuo Xian-Bo, Lv Zhao-Jie, Zhang Xue-Jun
Abstract excerpt
PURPOSE: To investigate associations between genetic variants involved in microRNA networks (microRNA biogenesis, microRNA and microRNA binding sites) and risk of gastric cancer. METHODS: We genotyped 19 SNPs of the microRNA-related genes in a case-control study of 311 gastric cancers and 425 cancer-free controls in a Chinese Han population. RESULTS: We found that two of the SNPs were significantly associated...
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