Article
Influence of common non-synonymous Toll-like receptor 4 polymorphisms on bronchopulmonary dysplasia and prematurity in human infants.
PloS one - 1 Jan 2012
Lavoie Pascal M, Ladd Mihoko, Hirschfeld Aaron F, Huusko Johanna, Mahlman Mari, Speert David P, Hallman Mikko, Lacaze-Masmonteil Thierry, Turvey Stuart E
Abstract excerpt
Bronchopulmonary dysplasia (BPD) is a common chronic lung disease and major risk factor for severe respiratory syncytial virus (RSV) infection among preterm infants. The Toll-like receptor 4 (TLR4) is involved in oxidative injury responses in the lungs. Two non-synonymous single nucleotide polymo...
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